# Electrophysiology

**URL:** https://forum.painresearcher.net/c/experimental-techniques/electrophysiology/17.md

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## [About the Electrophysiology category](https://forum.painresearcher.net/t/about-the-electrophysiology-category/247)

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**Author:** [@achamess](https://forum.painresearcher.net/u/achamess)\
**Replies:** 0

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This category is for all types of electrophysiology (patch-clamp, in vivo, field potentials, etc.)

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## [Probelm with Patch clamp of Dissociated DRG neurons](https://forum.painresearcher.net/t/probelm-with-patch-clamp-of-dissociated-drg-neurons/822)

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**Author:** [@Abderaouf](https://forum.painresearcher.net/u/Abderaouf)\
**Replies:** 7\
**Last updated:** [September 17, 2026, 6:50pm UTC](https://forum.painresearcher.net/t/probelm-with-patch-clamp-of-dissociated-drg-neurons/822 "2026-09-17T18:50:14Z")

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Hi everyone We are trying to study the electrophysiological parameters in dissociated DRG primary culture cells, we have been trying for a while now to get a whole cell configuration to do a patch clamp experiments but …

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## [Tips for spinal cord slices with dorsal roots attached?](https://forum.painresearcher.net/t/tips-for-spinal-cord-slices-with-dorsal-roots-attached/744)

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**Author:** [@james\_maks](https://forum.painresearcher.net/u/james_maks)\
**Replies:** 11\
**Last updated:** [September 8, 2020, 6:44pm UTC](https://forum.painresearcher.net/t/tips-for-spinal-cord-slices-with-dorsal-roots-attached/744 "2020-09-08T18:44:38Z")

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Hi everyone! I’m relatively new to the pain field and this has been an amazing resource for getting acquainted with techniques, papers, etc! So far, I can prepare good transverse spinal cord slices for patching but I’ve…

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## [Population datasets of neural activity in the DRG/dorsal horn?](https://forum.painresearcher.net/t/population-datasets-of-neural-activity-in-the-drg-dorsal-horn/509)

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**Author:** [@alex\_naka](https://forum.painresearcher.net/u/alex_naka)\
**Replies:** 2\
**Last updated:** [November 15, 2018, 7:22pm UTC](https://forum.painresearcher.net/t/population-datasets-of-neural-activity-in-the-drg-dorsal-horn/509 "2018-11-15T19:22:30Z")

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Hi all, I’m a newcomer to the pain field. Really loving this forum - incredible resource for getting oriented. I’m interested in trying to put together a quantitative model of the circuits/cell-types in the mouse dorsal…

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## [In Vivo Extracellular Recordings in Mouse Dorsal Horn - Anyone done it?](https://forum.painresearcher.net/t/in-vivo-extracellular-recordings-in-mouse-dorsal-horn-anyone-done-it/398)

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**Author:** [@achamess](https://forum.painresearcher.net/u/achamess)\
**Replies:** 2\
**Last updated:** [August 9, 2018, 10:01am UTC](https://forum.painresearcher.net/t/in-vivo-extracellular-recordings-in-mouse-dorsal-horn-anyone-done-it/398 "2018-08-09T10:01:26Z")

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I’m thinking about trying some field potential recordings in mouse DH. It seems like it’d be an approachable method to grossly measure electrical activity in the spinal cord from peripheral stimulation. Does anyone have …

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## [How to determine whether a drug's effect is presynaptic or postsynaptic?](https://forum.painresearcher.net/t/how-to-determine-whether-a-drugs-effect-is-presynaptic-or-postsynaptic/271)

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**Author:** [@achamess](https://forum.painresearcher.net/u/achamess)\
**Replies:** 6\
**Last updated:** [September 20, 2017, 2:10pm UTC](https://forum.painresearcher.net/t/how-to-determine-whether-a-drugs-effect-is-presynaptic-or-postsynaptic/271 "2017-09-20T14:10:03Z")

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Rookie question here: In slice electrophysiology, if you’re recording from a postsynaptic neuron and you perfuse a drug, how do you determine whether the effect of the drug is directly on the postsynaptic neuron from whi…

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## [Anyone use a Compresstome (Precisionary Instruments) for spinal cord slices?](https://forum.painresearcher.net/t/anyone-use-a-compresstome-precisionary-instruments-for-spinal-cord-slices/248)

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**Author:** [@achamess](https://forum.painresearcher.net/u/achamess)\
**Replies:** 0\
**Last updated:** [August 4, 2017, 2:28pm UTC](https://forum.painresearcher.net/t/anyone-use-a-compresstome-precisionary-instruments-for-spinal-cord-slices/248 "2017-08-04T14:28:31Z")

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Has anyone ever used this instrument for making spinal cord slices for electrophysiology? http://precisionary.com/ \[VF-300-side\_d400-300x210\] We have one in the lab this summer and I’m trying it out. It makes slices O…