# Astrocytes transduction in the spinal cord

**URL:** <https://forum.painresearcher.net/t/astrocytes-transduction-in-the-spinal-cord/465>\
**Category:** Experimental Techniques\
**Tags:** viral\_vectors\
**Created:** [August 9, 2018, 9:00pm UTC](https://forum.painresearcher.net/t/astrocytes-transduction-in-the-spinal-cord/465 "2018-08-09T21:00:51Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![thicunha](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/thicunha/32/386_2.png) [@thicunha](https://forum.painresearcher.net/u/thicunha)\
**Post date:** [August 9, 2018, 9:00pm UTC](https://forum.painresearcher.net/t/astrocytes-transduction-in-the-spinal-cord/465/1 "2018-08-09T21:00:51Z")

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Have one tried lentivirus for astrocytes transduction in the spinal cord? Could intrathecal injection be used? @rurongji, @achamess

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**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\
**Post date:** [August 10, 2018, 8:40pm UTC](https://forum.painresearcher.net/t/astrocytes-transduction-in-the-spinal-cord/465/2 "2018-08-10T20:40:36Z")

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Hey. I haven’t done this, but you might find this helpful:

> **[Preferential Lentiviral Targeting of Astrocytes in the Central Nervous System](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788778/)**
>
> The ability to visualize and genetically manipulate specific cell populations of the central nervous system (CNS) is fundamental to a better understanding of brain functions at the cellular and molecular levels. Tools to selectively target cells of...