# Compartmentalized DRG cultures in Xona Microfluid Chambers

**URL:** <https://forum.painresearcher.net/t/compartmentalized-drg-cultures-in-xona-microfluid-chambers/747>\
**Category:** Experimental Techniques\
**Created:** [September 4, 2020, 1:09pm UTC](https://forum.painresearcher.net/t/compartmentalized-drg-cultures-in-xona-microfluid-chambers/747 "2020-09-04T13:09:25Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\
**Post date:** [September 4, 2020, 1:09pm UTC](https://forum.painresearcher.net/t/compartmentalized-drg-cultures-in-xona-microfluid-chambers/747/1 "2020-09-04T13:09:25Z")

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Has anyone made compartmentalized cultures from adult DRG (6-8 weeks) using the Xona Microfluidics platform or something similar?

> **[Probing Functional Properties of Nociceptive Axons Using a Microfluidic...](https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0080722)**
>
> Pathological changes in axonal function are integral features of many neurological disorders, yet our knowledge of the molecular basis of axonal dysfunction remains limited. Microfluidic chambers (MFCs) can provide unique insight into the axonal...

[https://www.nature.com/articles/s41598-019-49214-w](https://www.nature.com/articles/s41598-019-49214-w)

> **[Building sensory axons: Delivery and distribution of NaV1.7 channels and...](https://advances.sciencemag.org/content/5/10/eaax4755?rss=1)**
>
> Sodium channel NaV1.7 controls firing of nociceptors, and its role in human pain has been validated by genetic and functional studies. However, little is known about NaV1.7 trafficking or membrane distribution along sensory axons, which can be a...