# Does anyone have experience using the FosCreERT2 (Luo) mouse in pain circuits (spinal cord, brain)?

**URL:** <https://forum.painresearcher.net/t/does-anyone-have-experience-using-the-foscreert2-luo-mouse-in-pain-circuits-spinal-cord-brain/262>\
**Category:** Reagents and Equipment\
**Created:** [September 1, 2017, 2:12pm UTC](https://forum.painresearcher.net/t/does-anyone-have-experience-using-the-foscreert2-luo-mouse-in-pain-circuits-spinal-cord-brain/262 "2017-09-01T14:12:48Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\
**Post date:** [September 1, 2017, 2:12pm UTC](https://forum.painresearcher.net/t/does-anyone-have-experience-using-the-foscreert2-luo-mouse-in-pain-circuits-spinal-cord-brain/262/1 "2017-09-01T14:12:48Z")

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Hi all,

Has anyone use this tamoxifen-inducible FosCreERT2 (Luo) mouse in the dorsal horn or higher areas for labeling of neurons activated by noxious stimuli? It looks interesting, although I have heard that it can lack in sensitivity depending on the area and stimulus.

[http://www.informatics.jax.org/allele/MGI:5488905](http://www.informatics.jax.org/allele/MGI:5488905)