# Paper: Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems (Chan et al. 2017) **URL:** \ **Category:** Uncategorized\ **Tags:** viral\_vectors\ **Created:** [August 3, 2017, 1:34pm UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239 "2017-08-03T13:34:23Z")\ **Posts on this page:** 6\ **Page:** 1
**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\ **Post date:** [August 3, 2017, 1:34pm UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/1 "2017-08-03T13:34:23Z")
[http://www.nature.com/neuro/journal/v20/n8/full/nn.4593.html](http://www.nature.com/neuro/journal/v20/n8/full/nn.4593.html) These viruses might be helpful for transducing DRG and the CNS more easily. I’ve got some to try out. I’ll let you know how it goes. @RPSeal @tberta ---
**Author:** ![snajjar](https://avatars.discourse-cdn.com/v4/letter/s/f1d935/32.png) [@snajjar](https://forum.painresearcher.net/u/snajjar)\ **Post date:** [August 7, 2017, 11:56am UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/2 "2017-08-07T11:56:08Z")
Are these available for order? @achamess ---
**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\ **Post date:** [August 7, 2017, 12:12pm UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/3 "2017-08-07T12:12:26Z")
You can order the plasmids on Addgene and make yourself. But the actual viruses can’t be bought at this time. ---
**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\ **Post date:** [August 7, 2017, 7:50pm UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/4 "2017-08-07T19:50:32Z")
See this. Looks like maybe not Addgene yet? > ---
**Author:** ![RPSeal](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/rpseal/32/577_2.png) [@RPSeal](https://forum.painresearcher.net/u/RPSeal)\ **Post date:** [November 1, 2017, 11:49am UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/5 "2017-11-01T11:49:16Z")
How did it go? Also where are you going after this? What will happen to this terrific website you’ve created? ---
**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\ **Post date:** [November 1, 2017, 12:40pm UTC](https://forum.painresearcher.net/t/paper-engineered-aavs-for-efficient-noninvasive-gene-delivery-to-the-central-and-peripheral-nervous-systems-chan-et-al-2017/239/6 "2017-11-01T12:40:38Z")
Hi @RPSeal. I haven’t injected yet. Been taking a break from experiments to write papers. But I’ll let you know if it works. I’m not skilled in tail vein injections so I’m going to ask one of my colleagues. The site is not going anywhere. I plan to keep it indefinitely. Thanks to sponsorship from companies like @compresstome, this site can continue to grow and bring value. Thanks for your encouragement and helping to promote this site.