# Sensory neuron-derived Nav1.7 contributes to dorsal horn neuron excitability

**URL:** <https://forum.painresearcher.net/t/sensory-neuron-derived-nav1-7-contributes-to-dorsal-horn-neuron-excitability/562>\
**Category:** Journal Club\
**Created:** [February 21, 2019, 7:43pm UTC](https://forum.painresearcher.net/t/sensory-neuron-derived-nav1-7-contributes-to-dorsal-horn-neuron-excitability/562 "2019-02-21T19:43:48Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\
**Post date:** [February 21, 2019, 7:43pm UTC](https://forum.painresearcher.net/t/sensory-neuron-derived-nav1-7-contributes-to-dorsal-horn-neuron-excitability/562/1 "2019-02-21T19:43:48Z")

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Nav1.7 trans-synaptically going from sensory neuron to DH neuron? Discuss.

> **[Sensory neuron-derived Nav1.7 contributes to dorsal horn neuron excitability](https://www.biorxiv.org/content/10.1101/551747v1?rss=1)**
>
> Expression of the voltage-gated sodium channel Nav1.7 in sensory neurons is required for pain sensation. We examined the role of Nav1.7 in the dorsal horn of the spinal cord using an epitope-tagged knock-in mouse. Immuno-electron microscopy showed...