# Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury

**URL:** <https://forum.painresearcher.net/t/spinal-macrophages-resolve-nociceptive-hypersensitivity-after-peripheral-injury/811>\
**Category:** Journal Club\
**Created:** [March 4, 2021, 5:17pm UTC](https://forum.painresearcher.net/t/spinal-macrophages-resolve-nociceptive-hypersensitivity-after-peripheral-injury/811 "2021-03-04T17:17:20Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![achamess](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.painresearcher.net/achamess/32/534_2.png) [@achamess](https://forum.painresearcher.net/u/achamess)\
**Post date:** [March 4, 2021, 5:17pm UTC](https://forum.painresearcher.net/t/spinal-macrophages-resolve-nociceptive-hypersensitivity-after-peripheral-injury/811/1 "2021-03-04T17:17:20Z")

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[https://www.cell.com/neuron/fulltext/S0896-6273(21)00118-5](https://www.cell.com/neuron/fulltext/S0896-6273(21)00118-5)

Exciting work from the Zylka lab

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**Author:** ![naratadam](https://avatars.discourse-cdn.com/v4/letter/n/838e76/32.png) [@naratadam](https://forum.painresearcher.net/u/naratadam)\
**Post date:** [April 12, 2021, 1:16am UTC](https://forum.painresearcher.net/t/spinal-macrophages-resolve-nociceptive-hypersensitivity-after-peripheral-injury/811/2 "2021-04-12T01:16:50Z")

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The whole CNS macrophage idea (and the challenging of CNS immune privilege) is really throwing me into a loop. Also interesting they saw the “sham” had a phenotype that was different than nerve injury.