cAMP signaling in dorsal root ganglion

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Hi all,
I would like to measure cAMP signaling in DRGs isolated from mice. Has anyone used fluorescence-based assays to measure cAMP in DRGs?

Thank you in advance.
Regards,
Bishir.

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Hi @BishirM, we have evaluated cAMP in DRG cultures and DRGs tissue (ex-vivo). Please see the methods in the following paper: Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons | Nature Neuroscience

1 Like
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Thank you so much @thicunha. The paper is really helpful. Congratulations for this amazing work.

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Here is a paper I just saw