TMEM119 Cre ERT2

Hi guys,

Has anyone crossed the TMEM119 Cre ERT2 line with Rosa IDTR line to try to deplete microglia? Similar to the CX3CR1 line but should be more specific. We’ve done so with some success, but one of our collaborators hasn’t had the same success so we are now in the midst of repeating it. Just wanted to see if anyone else has tried and is also having problems/successes with this cross…

@achamess @tberta

We have used this line only to label microglia with tdTomato, but we had consistent results every time.

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